Hemodynamic nonlinearities affect BOLD fMRI response timing and amplitude
نویسندگان
چکیده
منابع مشابه
Hemodynamic scaling of fMRI-BOLD signal amplitude in normal aging
Introduction: Vascular reactivity and resting cerebral blood flow (CBF) levels lead to inter-subject variability in functional magnetic resonance imaging (fMRI) studies using the Blood Oxygen Level Dependent (BOLD) contrast to a neural task. This variability is exacerbated in an aging population [1]. Hemodynamic scaling using Resting State Fluctuation Amplitude (RSFA) or Breath hold (BH) can mi...
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One of the current topics of research in neuroimaging techniques is related to explaining and modelling the Blood Oxygen Level Dependent (BOLD) responses. BOLD responses are estimated by processing functional Magnetic Resonance Imaging (fMRI) data. BOLD responses are caused by hemodynamic responses to neural activity which alter the levels of blood oxygenation at local brain regions. The main a...
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Non-linear hemodynamic models express the BOLD signal as a nonlinear, parametric functional of the temporal sequence of local neural activity. Several models have been proposed for this neural activity. We identify one such parametric model by estimating the distribution of its parameters. These distributions are themselves stochastic, therefore we estimate their variance by epoch based leave-o...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2009
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2009.06.001